===================================================================== ===================================================================== We propose to use ISOCAM and ISOPHOT to study phenomena at the interface between the High Energy Astrophysics and the Physics of Cold Interstellar Gas. If an X-ray binary is inside or near a molecular cloud most of the energy from the relativistic particles streaming out from the compact source must be dissipated by heating of the interstellar material and thermal emission from dust is expected. The radio ears in W50 (which are brightened by particles streaming out from the classic microquasar SS433), and the runaway binary Circinus X-1 (which is moving through the interstellar medium at a speed of several hundred km/s) are appropriate to study these phenomena. Other sources of study are the high mass X-ray binary Cygnus X-1 and the superluminal microquasar.